Lymphocytic Choriomeningitis

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Lymphocytic Choriomeningitis

Lymphocytic choriomeningitis virus (LCMV) is a pathogen, normally carried in rodents, which can cause aseptic meningitis and other conditions in humans. Most people experience a relatively mild illness and fatal infections are rare; however, pregnant women may give birth to congenitally infected infants with severe defects of the brain and eye. In a few instances, this virus has been transmitte...

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Lymphocytic Choriomeningitis Virus

There has been an upsurge of interest in lymphocytic choriomeningitis virus (LCMV) as a human pathogen and specifically as an underdiagnosed congenital infection (1,2). LCMV is a member of the Arenaviridae family of viruses. Arenaviruses have a complex life cycle involving chronic infection and shedding of the virus in rodents and episodic infections in humans (3,4). Six of the arenaviruses (La...

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Lymphocytic Choriomeningitis in Michigan

We summarize the first reported case of acquired lymphocytic choriomeningitis virus (LCMV) infection in Michigan to be investigated by public health authorities and provide evidence of the focal nature of LCMV infection in domestic rodents. Results of serologic and virologic testing in rodents contrasted, and negative serologic test results should be confirmed by tissue testing.

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Relationship of the Anti-lymphocytic Choriomeningitis Immune Response to Tissue Injury in Chronic Lymphocytic Choriomeningitis

The possibility of an immunologic basis for the tissue injury associated with persistent lymphocytic choriomeningitis (LCM) 1 viral infection in mice is suggested by several pieces of evidence. First, chronic LCM infection per se usually is not associated with cytopathogenicity. Mice persistently infected with LCM (LCM carriers) of most strains demonstrate high titers of virus in virtally all t...

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ژورنال

عنوان ژورنال: BMJ

سال: 1951

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.1.4718.1298